cAbl tyrosine kinase mediates reactive oxygen species- and caveolin-dependent AT1 receptor signaling in vascular smooth muscle: role in vascular hypertrophy: Retraction.
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چکیده
The Emory University Investigation Committee conducted an institutional investigation of fraudulent data published in Ushio-Fukai et al. Circ Res 2005;97:829–836. Emory University Office of Research Compliance reported that Dr. Lian Zuo admitted to the Emory University Investigation Committee to falsifying Figures 2A top panel, 3C top panel, 3C bottom panel, 4A top panel, 5B top panel right, 5B bottom panel left, and 5B bottom panel right. The Emory Investigation Committee reported it found evidence to conclude that the following figures were also falsified by Dr. Lian Zuo: 1A top and lower panels, 3A top panel, 3A second panel, 3A bottom panel, 3B bottom panel, 4C bottom panel, and 6A top and bottom panels. The Emory University Investigation Committee also reported it found Figures 2A bottom panel, 2B bottom panel, 3B top panel, 4B bottom panel, 4D bottom panel, 5A middle panel, and 6B bottom panel to be falsified, but the Committee was unable to determine who was responsible for the falsification.
منابع مشابه
Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophy.
OBJECTIVE Angiotensin II (Ang II) is a potent mediator of vascular hypertrophy in vascular smooth muscle cells (VSMCs). These effects are mediated through the Ang II type 1 receptor (AT1R) and require its trafficking through caveolin-1 (Cav1)-enriched lipid rafts and reactive oxygen species (ROS) derived from Rac1-dependent NAD(P)H oxidase. The specific role(s) of Cav1 in AT1R signaling is inco...
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عنوان ژورنال:
- Circulation research
دوره 106 11 شماره
صفحات -
تاریخ انتشار 2010